Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003182 | 0.83 | F2 (0.60) | F2 | |
| Hydrochloric Acid SCHEMBL9002826 | 0.83 | F2 (0.60) | F2 | |
| Hydrochloric Acid SCHEMBL7391780 | 0.82 | F2 (0.57) | F2 | |
| SCHEMBL7306964 | 0.81 | F2 (0.60) | F2NPY5R | |
| SCHEMBL7389450 | 0.81 | F2 (0.59) | F2 | |
| Acetic Acid SCHEMBL8947746 | 0.81 | F2 (0.58) | F2NPY5R | |
| Hydrochloric Acid SCHEMBL9002788 | 0.81 | F2 (0.60) | F2 | |
| Acetic Acid SCHEMBL8947565 | 0.79 | F2 (0.53) | F2 | |
| Acetic Acid SCHEMBL8947715 | 0.77 | F2 (0.49) | F2 | |
| SCHEMBL7305122 | 0.77 | F2 (0.59) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559046-B1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| EP-0559046-A1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-09-08 | — | — | EP | disclosed |