Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.77 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290379 | 0.92 | F2 (0.73) | F2KCNA5KCNH2 | |
| Sulfurous Acid SCHEMBL7295109 | 0.90 | F2 (0.95) | F2 | |
| Sulfurous Acid SCHEMBL7292725 | 0.90 | F2 (0.95) | F2 | |
| Sulfurous Acid SCHEMBL7294729 | 0.90 | F2 (0.95) | F2 | |
| SCHEMBL7290540 | 0.86 | F2 (0.64) | F2KCNA5KCNH2 | |
| Sulfurous Acid SCHEMBL7300543 | 0.86 | F2 (0.60) | F2KCNA5 | |
| SCHEMBL8972382 | 0.84 | F2 (0.65) | F2KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL8919175 | 0.84 | F2 (0.96) | F2 | |
| Hydrochloric Acid SCHEMBL7293421 | 0.84 | F2 (0.96) | F2 | |
| Sulfurous Acid SCHEMBL8920332 | 0.84 | F2 (0.83) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468231-B1 | Guanidins | HOFFMANN LA ROCHE (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0468231-A2 | Guanidins | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-29 | — | — | EP | disclosed |