SCHEMBL729893

SCHEMBL729893

CCO[Si](CCCCCCNC(N)=O)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.40
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
PAOX Q6QHF9 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CASP2 P42575 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
FAAH O00519 1/20 0.32
TSHR P16473 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728058 0.97 EPHX1 (0.40) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL728329 0.93 EPHX1 (0.34) EPHX1CA12CA1CA2CA9
SCHEMBL3913343 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL3920594 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL3912394 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL1142988 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL3908696 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL3909262 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL3912395 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12
SCHEMBL730236 0.92 EPHX1 (0.39) EPHX1KDM4EMAPK1HIF1ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed