Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7306625 | 0.90 | F2 (0.43) | F2ALDH1A1 | |
| SCHEMBL8947691 | 0.89 | F2 (0.55) | F2 | |
| SCHEMBL7305122 | 0.87 | F2 (0.59) | F2 | |
| SCHEMBL7303162 | 0.85 | F2 (0.44) | F2 | |
| SCHEMBL7294199 | 0.84 | F2 (0.44) | F2ALDH1A1 | |
| SCHEMBL7294950 | 0.83 | F2 (0.37) | F2 | |
| SCHEMBL7296699 | 0.83 | F2 (0.52) | F2 | |
| SCHEMBL7297455 | 0.83 | F2 (0.41) | F2 | |
| Acetic Acid SCHEMBL8719961 | 0.82 | F2 (0.50) | F2 | |
| Hydrochloric Acid SCHEMBL8716407 | 0.81 | F2 (0.59) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559046-B1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0559046-A1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-09-08 | — | — | EP | disclosed |