Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290534 | 0.80 | HTR2C (0.43) | — | |
| SCHEMBL7300098 | 0.79 | — | — | |
| SCHEMBL7298699 | 0.79 | HTR2C (0.42) | — | |
| SCHEMBL7294341 | 0.78 | — | — | |
| SCHEMBL7298517 | 0.78 | KMT2A (0.31) | — | |
| SCHEMBL7298536 | 0.76 | KDM4E (0.35) | — | |
| SCHEMBL7290525 | 0.74 | P2RY1 (0.33) | BACE1 | |
| SCHEMBL7297056 | 0.72 | TDP1 (0.41) | — | |
| SCHEMBL7293354 | 0.71 | HTR2C (0.42) | HCAR3HCAR2 | |
| SCHEMBL17193997 | 0.70 | MAOB (0.37) | PKMPKLRMAOBHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |