Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7989047 | 0.99 | F2 (0.40) | F2PRSS1PRSS2PRSS3ADORA2A | |
| SCHEMBL7301539 | 0.91 | F2 (0.37) | F2PRSS1PRSS2PRSS3CYP2D6 | |
| SCHEMBL7292153 | 0.91 | F2 (0.37) | F2PRSS1PRSS2PRSS3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7992390 | 0.90 | F2 (0.36) | F2PRSS1PRSS2PRSS3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7992549 | 0.90 | F2 (0.36) | F2PRSS1PRSS2PRSS3CYP2D6 | |
| SCHEMBL7003541 | 0.90 | F2 (0.42) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7297314 | 0.87 | F2 (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7003544 | 0.87 | MEN1 (0.32) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL7978162 | 0.86 | F2 (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7000162 | 0.83 | KMT2A (0.43) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069132-A1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-01-17 | — | — | EP | disclosed |