Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.82 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8918172 | 0.99 | F2 (0.82) | F2MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL8574630 | 0.99 | F2 (0.82) | F2MMP9MMP2 | |
| SCHEMBL8576183 | 0.95 | F2 (0.74) | F2MMP9MMP2 | |
| SCHEMBL8605421 | 0.95 | F2 (0.74) | F2MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL7292719 | 0.93 | F2 (0.83) | F2MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL8918877 | 0.93 | F2 (0.83) | F2MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL8921529 | 0.90 | F2 (0.77) | F2 | |
| Hydrochloric Acid SCHEMBL8575872 | 0.90 | F2 (0.77) | F2 | |
| Hydrochloric Acid SCHEMBL8917710 | 0.90 | F2 (0.79) | F2MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL7300246 | 0.90 | F2 (0.79) | F2MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | claimed |
| EP-0468231-B1 | Guanidins | HOFFMANN LA ROCHE (CH) | 1994-09-21 | — | — | EP | claimed |
| US-5260307-A | Inhibit thrombin-induced platlet aggregation and clotting of fibrogen in plasma | HOFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | claimed |
| US-5763436-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5595999-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1997-01-21 | — | — | US | disclosed |
| US-5583133-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-12-10 | — | — | US | disclosed |
| US-5532232-A | INHIBIT THROMBIN INDUCED PLATELET AGGREGATION; FIBRINOGEN ANTICOAGULANTS IN BLOOD | HOFFMANN-LA ROCHE INC. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5260307-A | Inhibit thrombin-induced platlet aggregation and clotting of fibrogen in plasma | HOFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |