Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.64 |
| ▸ | REN | P00797 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PEPD | P12955 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290125 | 0.95 | ACE (0.67) | ACERENKDM4EF2LMNA | |
| SCHEMBL6786935 | 0.88 | ACE (0.80) | ACERENKDM4EF2LMNA | |
| SCHEMBL7287908 | 0.86 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL7292619 | 0.85 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL6788835 | 0.82 | ACE (0.85) | ACERENKDM4EF2LMNA | |
| Tumonoic Acid D SCHEMBL29885139 | 0.82 | ACE (0.70) | ACERENKDM4EF2LMNA | |
| SCHEMBL13963507 | 0.82 | ACE (0.70) | ACERENKDM4EF2LMNA | |
| SCHEMBL21886585 | 0.82 | ACE (0.70) | ACERENKDM4EF2LMNA | |
| SCHEMBL10982207 | 0.79 | ACE (0.62) | ACERENKDM4EF2LMNA | |
| SCHEMBL11558222 | 0.78 | ACE (1.00) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915088-B1 | D-Proline derivatives | HOFFMANN LA ROCHE (CH) | 2002-09-18 | — | — | EP | claimed |