Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772649 | 0.85 | MEN1 (0.59) | MEN1KMT2AHTTSMN1; SMN2GAA | |
| SCHEMBL23087216 | 0.77 | MEN1 (0.66) | MEN1KMT2AHTTCYP1A2CYP2C19 | |
| SCHEMBL31437520 | 0.76 | CSNK2A1 (0.40) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL24483849 | 0.75 | MEN1 (0.39) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL4910016 | 0.75 | KMT2A (0.63) | MEN1KMT2AHTTSMN1; SMN2GAA | |
| SCHEMBL13002938 | 0.74 | — | — | |
| SCHEMBL14281214 | 0.72 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL14710744 | 0.71 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL4911425 | 0.71 | MEN1 (0.61) | MEN1KMT2AHTTSMN1; SMN2GAA | |
| SCHEMBL24553896 | 0.71 | HTT (0.50) | KMT2AHTTSMN1; SMN2GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604353-B1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-07-01 | — | — | EP | disclosed |
| US-5441969-A | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1995-08-15 | — | — | US | disclosed |
| EP-0604353-A1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1994-06-29 | — | — | EP | disclosed |