Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PYGL | P06737 | 1/20 | 0.55 |
| ▸ | PYGM | P11217 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655142 | 0.89 | MAPT (0.60) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9401939 | 0.87 | CACNA1F (0.66) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7448031 | 0.84 | CYP1A2 (0.64) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29926641 | 0.84 | CYP1A2 (0.64) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11688678 | 0.84 | CYP1A2 (0.55) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7400360 | 0.84 | CYP1A2 (0.64) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11688660 | 0.84 | CYP1A2 (0.55) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7272138 | 0.83 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7421240 | 0.83 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7266605 | 0.83 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | disclosed |