Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300577 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2CASP3RAB9ASENP8 | |
| Hydrochloric Acid SCHEMBL7212393 | 0.99 | MAPT (0.46) | MAPTSMN1; SMN2CASP3RAB9ASENP8 | |
| Hydrochloric Acid SCHEMBL7212388 | 0.99 | MAPT (0.46) | MAPTSMN1; SMN2CASP3RAB9ASENP8 | |
| SCHEMBL7308575 | 0.88 | FNTA (0.44) | MAPTSMN1; SMN2CASP3RAB9ASENP8 | |
| SCHEMBL7308567 | 0.88 | FNTA (0.44) | MAPTSMN1; SMN2CASP3RAB9ASENP8 | |
| SCHEMBL7307971 | 0.88 | SETD7 (0.49) | MAPTSMN1; SMN2ALDH1A1HTTSETD7 | |
| SCHEMBL7307975 | 0.88 | SETD7 (0.49) | MAPTSMN1; SMN2ALDH1A1HTTSETD7 | |
| SCHEMBL9591365 | 0.83 | SETD7 (0.45) | MAPTSMN1; SMN2ALDH1A1HTTSETD7 | |
| SCHEMBL9591372 | 0.83 | SETD7 (0.45) | MAPTSMN1; SMN2ALDH1A1HTTSETD7 | |
| SCHEMBL7303180 | 0.82 | SETD7 (0.48) | MAPTALDH1A1SETD7LMNAPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |