Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300747 | 1.00 | DPP7 (0.46) | DPP7DPP4RECQLDPP8XPNPEP1 | |
| Hydrochloric Acid SCHEMBL6768517 | 0.99 | DPP7 (0.45) | DPP7DPP4RECQLDPP8XPNPEP1 | |
| Hydrochloric Acid SCHEMBL6768519 | 0.99 | DPP7 (0.45) | DPP7DPP4RECQLDPP8XPNPEP1 | |
| SCHEMBL7300149 | 0.84 | DPP7 (0.48) | DPP7DPP4DPP8 | |
| SCHEMBL7300144 | 0.84 | DPP7 (0.48) | DPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6772849 | 0.83 | DPP7 (0.47) | DPP7DPP4DPP8 | |
| SCHEMBL7300262 | 0.83 | DPP7 (0.35) | DPP7DPP4DPP8 | |
| SCHEMBL7300257 | 0.83 | DPP7 (0.35) | DPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6772855 | 0.83 | DPP7 (0.47) | DPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL6767080 | 0.82 | DPP7 (0.34) | DPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |