Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308835 | 0.90 | PDE5A (0.76) | PDE5A | |
| SCHEMBL7306609 | 0.88 | PDE5A (0.79) | PDE5A | |
| SCHEMBL7307495 | 0.87 | PDE5A (0.80) | PDE5A | |
| SCHEMBL7306518 | 0.86 | PDE5A (0.70) | PDE5A | |
| SCHEMBL5698551 | 0.86 | PDE5A (1.00) | PDE5A | |
| SCHEMBL7297768 | 0.86 | PDE5A (0.75) | PDE5A | |
| SCHEMBL7309949 | 0.85 | PDE5A (1.00) | PDE5A | |
| SCHEMBL7305663 | 0.85 | PDE5A (0.76) | PDE5A | |
| SCHEMBL7306551 | 0.84 | PDE5A (0.67) | PDE5A | |
| SCHEMBL7299762 | 0.84 | PDE5A (1.00) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636626-A1 | Pyrazolopyrimidine Derivatives | LABORATOIRES GLAXO SA (FR) | 1995-02-01 | — | — | EP | disclosed |