Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PREP | P48147 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302353 | 0.86 | PREP (0.44) | ACECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7436192 | 0.74 | PREP (0.45) | PREP | |
| SCHEMBL7297537 | 0.73 | PREP (0.45) | CHRM2CHRM4CHRM1CHRM3PREP | |
| SCHEMBL5742212 | 0.70 | ACE (0.60) | ACEF2 | |
| SCHEMBL5742215 | 0.70 | ACE (0.60) | ACEF2 | |
| SCHEMBL5741139 | 0.69 | ACE (0.59) | ACEF2 | |
| SCHEMBL5741144 | 0.69 | ACE (0.59) | ACEF2 | |
| SCHEMBL7293607 | 0.67 | PREP (0.54) | ACECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7303049 | 0.67 | CHRM2 (0.59) | ACECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6782705 | 0.64 | ACE (0.72) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |