Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 8/20 | 0.69 |
| ▸ | ACACB | O00763 | 2/20 | 0.64 |
| ▸ | ACACA | Q13085 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293044 | 0.91 | ACACB (0.64) | CXCR1ACACBACACARAB9ANPC1 | |
| SCHEMBL7327061 | 0.90 | ACACB (0.62) | CXCR1ACACBACACARAB9ANPC1 | |
| SCHEMBL7295131 | 0.80 | ACACB (0.97) | ACACBACACARAB9ANPC1MAPK1 | |
| SCHEMBL7292052 | 0.78 | ACACB (0.62) | CXCR1ACACBACACARAB9ANPC1 | |
| SCHEMBL17233279 | 0.78 | ACACB (0.73) | ACACBACACARAB9ANPC1MAPK1 | |
| SCHEMBL3503745 | 0.77 | ACACB (0.61) | ACACBACACAKDM4EHRH3ALDH1A1 | |
| SCHEMBL18598419 | 0.77 | ACACB (0.71) | ACACBACACARAB9ANPC1MAPK1 | |
| SCHEMBL7291741 | 0.76 | HPGD (0.64) | ACACBACACARAB9AKDM4EMAPK1 | |
| SCHEMBL23588222 | 0.76 | ACACB (0.70) | CXCR1ACACBACACARAB9ANPC1 | |
| SCHEMBL7302028 | 0.76 | ACACB (0.70) | ACACBACACARAB9ANPC1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5356916-A | Treating Parkinson*s disease | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |