Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744998 | 0.84 | PDCD4 (0.40) | PDCD4NAAA | |
| SCHEMBL9326398 | 0.82 | PDCD4 (0.39) | PDCD4NAAA | |
| SCHEMBL9745643 | 0.81 | PDCD4 (0.38) | PDCD4CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9766934 | 0.81 | PDCD4 (0.37) | PDCD4CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL7296014 | 0.79 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9325205 | 0.77 | PDCD4 (0.41) | PDCD4NAAA | |
| SCHEMBL7294590 | 0.77 | PDCD4 (0.47) | PDCD4NAAA | |
| SCHEMBL8985076 | 0.77 | PDCD4 (0.47) | PDCD4NAAA | |
| SCHEMBL14339054 | 0.77 | PDCD4 (0.47) | PDCD4NAAA | |
| SCHEMBL9671381 | 0.77 | PDCD4 (0.47) | PDCD4NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376676-A | Process of using anti-inflammatory furanones as selective calcium channel inhibitors | ALLERGAN, INC. (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0372940-A2 | Anti-inflammatory 2-furanones | ALLERGAN, INC (US) | 1990-06-13 | — | — | EP | disclosed |