Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.64 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.64 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301538 | 1.00 | DPP4 (0.64) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6766584 | 0.99 | DPP4 (0.62) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6766586 | 0.99 | DPP4 (0.62) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL7299412 | 0.96 | DPP4 (0.63) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL7299409 | 0.96 | DPP4 (0.63) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6766564 | 0.95 | DPP4 (0.61) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6766559 | 0.95 | DPP4 (0.61) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL7289498 | 0.91 | DPP7 (0.61) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL7289506 | 0.91 | DPP7 (0.61) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL6766509 | 0.90 | DPP7 (0.59) | DPP4DPP7DPP8DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |