1,4-Butanediol

1,4-Butanediol

SCHEMBL730176

CC(CO)CO.OCCCCO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
TRPA1 O75762 2/20 0.32
GPR84 Q9NQS5 1/20 0.30
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28120553 0.97 TSHR (0.47) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL28114210 0.97 TSHR (0.47) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
1,5-Pentanediol SCHEMBL14471864 0.97 TSHR (0.47) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
1,4-Butanediol SCHEMBL28204083 0.94 TSHR (0.48) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
1,3-Propanediol SCHEMBL7714427 0.93 TSHR (0.45) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
Ethylene Glycol SCHEMBL5715504 0.85 TSHR (0.50) TSHRLMNAALDH1A1MEN1KMT2A
SCHEMBL20756 0.84
SCHEMBL9085447 0.84
SCHEMBL18136332 0.84
SCHEMBL2161697 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106854272-A Continous way antiskid chain transparent polyurethane elastomer and preparation method thereof 山东诺威聚氨酯股份有限公司 2017-06-16 CN claimed
EP-3790917-B1 EPOXY RESIN BASED CATHODIC DIP COATING (KTL) OF METAL COMPONENTS AS ADHESION PROMOTERS FOR PU SYSTEMS BASF POLYURETHANES GMBH (DE) 2023-08-02 EP disclosed
CN-112105668-B Cathode dip coating (KTL) based epoxy resins for metal parts as PU system adhesion promoters 巴斯夫聚氨酯有限责任公司 2023-07-21 CN disclosed
EP-2984119-B1 RESIN FOR TONER AND TONER CANON KK (JP) 2021-12-22 EP disclosed
US-20210246319-A1 EPOXY RESIN-BASED CATHODIC ELECTRODEPOSITION (CED) OF METAL COMPONENTS AS AN ADHESION PROMOTER FOR PU SYSTEMS BASF POLYURETHANES GMBH (DE) 2021-08-12 US disclosed
EP-3790917-A1 EPOXY RESIN-BASED CATHODIC DIP COATING (CDC) OF METAL COMPONENTS AS AN ADHESION PROMOTER FOR PU SYSTEMS BASF Polyurethanes GmbH (DE) 2021-03-17 EP disclosed
WO-2019215119-A1 EPOXY RESIN-BASED CATHODIC DIP COATING (CDC) OF METAL COMPONENTS AS AN ADHESION PROMOTER FOR PU SYSTEMS BASF POLYURETHANES GMBH (DE) 2019-11-14 WO disclosed
US-20190235134-A1 ANTIREFLECTION FILM, POLARIZING PLATE, IMAGE DISPLAY DEVICE, ANTIREFLECTION PRODUCT, METHOD OF MANUFACTURING LAMINATE, AND METHOD OF MANUFACTURING ANTIREFLECTION FILM FUJIFILM CORPORATION (JP) 2019-08-01 US disclosed
EP-2984118-B1 TONER AND METHOD FOR PRODUCING THE TONER CANON KK (JP) 2018-02-21 EP disclosed
EP-2985303-B1 TONER RESIN AND TONER CANON KK (JP) 2017-09-20 EP disclosed
US-8138299-B2 Hardness below 80 Shore A; preferably transparent and plasticizer-free; Polyesterurethane made by reacting an isocyanate with two polyesterdiols, the first having 1,4-butanediol units and another C5+ diol, and the second having 1,4-butanediol units and a C2-3 diol such as ethylene glycol; nonshrinking BASF AKTIENGESELLSCHAFT (DE) 2012-03-20 US disclosed
US-20090127921-A1 PROCESS FOR THE PRODUCTION OF CELLULAR POLYURETHANE (PUR) CASTING ELASTOMERS FROM STORAGE-STABLE 1,5-NAPHTHALENEDIISOCYANATE (NDI) PREPOLYMERS BAYER MATERIALSCIENCE AG (DE) 2009-05-21 US disclosed
US-20080194789-A1 Thermoplastic Polyurethanes BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-6857626-B2 Spring element BASF AKTIENGESELLSCHAFT (DE) 2005-02-22 US disclosed
WO-2005012435-A1 ELECTRICALLY CONDUCTIVE, FLAME RETARDANT FILLERS, METHOD OF MANUFACTURE, AND USE THEREOF WORLD PROPERTIES, INC. (US) 2005-02-10 WO disclosed
US-20040075204-A1 Spring element BASF AKTIENGESELLSCHAFT (DE) 2004-04-22 US disclosed
US-20030132561-A1 Spring element BASF AKTIENGESELLSCHAFT (DE) 2003-07-17 US disclosed
US-20020111520-A1 HYDROFORMYLATION PROCESS LYONDELL CHEMICAL TECHNOLOGY, LP 2002-08-15 US disclosed
US-6426437-B1 Hydroformylation process ARCO CHEMICAL TECHNOLOGY, L.P. 2002-07-30 US disclosed
US-20020041791-A1 Connecting element BASF AKTIENGESELLSCHAFT (DE) 2002-04-11 US disclosed