Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294777 | 1.00 | PREP (0.77) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7297629 | 0.96 | PREP (0.76) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7295355 | 0.95 | PREP (0.78) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7295850 | 0.89 | PREP (0.62) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7301847 | 0.87 | PREP (1.00) | PREP | |
| SCHEMBL7298779 | 0.87 | PREP (1.00) | PREP | |
| SCHEMBL7295370 | 0.86 | PREP (0.71) | PREPACEALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL7296291 | 0.85 | PREP (0.96) | PREP | |
| SCHEMBL7294462 | 0.84 | PREP (0.75) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7294125 | 0.84 | PREP (0.75) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |