Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302362 | 1.00 | MEN1 (0.45) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL7301163 | 0.83 | MEN1 (0.48) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL7301151 | 0.83 | MEN1 (0.48) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL7309334 | 0.82 | PREP (0.65) | RAB9AKMT2APREP | |
| SCHEMBL7308507 | 0.82 | PREP (0.65) | RAB9AKMT2APREP | |
| SCHEMBL7297939 | 0.82 | PREP (0.65) | RAB9AKMT2APREP | |
| SCHEMBL7297933 | 0.82 | PREP (0.65) | RAB9AKMT2APREP | |
| SCHEMBL7297462 | 0.81 | MEN1 (0.49) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL7297456 | 0.81 | MEN1 (0.49) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL7297823 | 0.80 | PREP (0.38) | MEN1KMT2APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |