Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296800 | 0.87 | CARM1 (0.43) | KCNH2HRH3MEN1KMT2AOPRM1 | |
| SCHEMBL7295738 | 0.80 | ATM (0.51) | MEN1KMT2A | |
| SCHEMBL27596675 | 0.80 | KCNH2 (0.50) | KCNH2HRH3MEN1KMT2AOPRM1 | |
| SCHEMBL7296229 | 0.79 | CA1 (0.45) | MEN1KMT2A | |
| SCHEMBL7296235 | 0.79 | CA1 (0.45) | MEN1KMT2A | |
| SCHEMBL5888726 | 0.78 | MEN1 (0.58) | KCNH2HRH3MEN1KMT2AOPRM1 | |
| SCHEMBL9728079 | 0.76 | ACE (0.46) | — | |
| SCHEMBL20250837 | 0.74 | KCNH2 (0.59) | KCNH2MEN1KMT2A | |
| SCHEMBL29950879 | 0.74 | KCNH2 (0.51) | KCNH2HRH3MEN1KMT2A | |
| SCHEMBL7295507 | 0.74 | CNR2 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164388-A | Hypotensive agents, treatment of congestive heart failure | ABBOTT LABORATORIES (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0365992-A1 | Heterocyclic peptide renin inhibitors | ABBOTT LABORATORIES (US) | 1990-05-02 | — | — | EP | disclosed |