Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 17/20 | 0.72 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | CPT2 | P23786 | 1/20 | 0.44 |
| ▸ | CPT1A | P50416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303286 | 1.00 | PREP (0.72) | PREPCYP26A1CPT2CPT1A | |
| SCHEMBL7296561 | 0.89 | PREP (0.75) | PREP | |
| SCHEMBL7433434 | 0.89 | PREP (0.75) | PREP | |
| SCHEMBL7302011 | 0.89 | PREP (0.55) | PREPCYP26A1 | |
| SCHEMBL7299353 | 0.88 | PREP (0.54) | PREPCYP26A1 | |
| SCHEMBL7296556 | 0.86 | PREP (0.53) | PREPCPT2CPT1A | |
| SCHEMBL5582561 | 0.85 | CYP26A1 (0.53) | PREPCYP26A1 | |
| SCHEMBL7303569 | 0.84 | PREP (1.00) | PREP | |
| SCHEMBL8153998 | 0.84 | PREP (1.00) | PREP | |
| SCHEMBL7297437 | 0.84 | PREP (1.00) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017929-A | Cholinesterase activator | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0754454-A1 | CHOLINESTERASE ACTIVATOR | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |