Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | GBA1 | P04062 | 6/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 13/20 | 0.32 |
| ▸ | UGCG | Q16739 | 3/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
| ▸ | AGL | P35573 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302002 | 1.00 | GAA (0.41) | GAAGBA1GBA2UGCGMGAM | |
| SCHEMBL2436668 | 0.89 | GBA2 (0.44) | GAAGBA1GBA2UGCGMGAM | |
| SCHEMBL4540594 | 0.87 | GBA2 (0.45) | GAAGBA1GBA2UGCG | |
| SCHEMBL12513136 | 0.84 | GAA (0.37) | GAA | |
| SCHEMBL7307249 | 0.84 | GAA (0.37) | GAA | |
| SCHEMBL7302558 | 0.84 | GAA (0.37) | GAA | |
| SCHEMBL7303785 | 0.84 | GAA (0.37) | GAA | |
| SCHEMBL7301100 | 0.84 | GAA (0.37) | GAA | |
| SCHEMBL7311736 | 0.81 | — | — | |
| SCHEMBL7307381 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481756-B1 | Benzamide derivatives | TEIKOKU CHEM IND CO LTD (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5143935-A | Gastrointestinal disorders | TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0481756-A2 | Benzamide derivatives | TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |