Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139538 | 1.00 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AADRA1A | |
| SCHEMBL11414508 | 1.00 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AADRA1A | |
| SCHEMBL9094272 | 1.00 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AADRA1A | |
| Water SCHEMBL11587520 | 0.98 | KDM4C (0.49) | KDM4CKDM4APHF8KDM2AADRA1A | |
| Bromide SCHEMBL11779655 | 0.98 | KDM4C (0.49) | KDM4CKDM4APHF8KDM2AADRA1A | |
| SCHEMBL11932533 | 0.92 | KDM4C (0.44) | KDM4CKDM4APHF8KDM2ABLM | |
| SCHEMBL27087764 | 0.91 | EPHX2 (0.45) | KDM4CKDM4APHF8KDM2ABLM | |
| Water SCHEMBL20401200 | 0.90 | EPHX2 (0.44) | KDM4CKDM4APHF8KDM2ABLM | |
| SCHEMBL11424767 | 0.86 | KDM4C (0.53) | KDM4CKDM4APHF8KDM2AADRA1A | |
| SCHEMBL11417162 | 0.86 | KDM4C (0.57) | KDM4CKDM4APHF8KDM2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575844-B1 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | EP | disclosed |
| EP-0575844-A2 | Hydroxamic acid derivatives and pharmaceutical compositions thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-29 | — | — | EP | disclosed |