Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 6/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 10/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319109 | 0.91 | PPARG (0.55) | PPARGABL1CYP1B1MAPTEGFR | |
| SCHEMBL7315053 | 0.89 | MAPT (0.62) | PPARGKDM5ACYP1B1ABCB1MAPT | |
| SCHEMBL7306588 | 0.88 | PPARG (0.57) | PPARGABL1CYP1B1MAPTEGFR | |
| SCHEMBL7313546 | 0.88 | PPARG (0.57) | PPARGABL1CYP1B1MAPTEGFR | |
| SCHEMBL7316873 | 0.87 | CYP1B1 (0.57) | PPARGABL1CYP1B1MAPTEGFR | |
| SCHEMBL7311118 | 0.87 | CYP1B1 (0.57) | PPARGCYP1B1MAPT | |
| SCHEMBL7317205 | 0.86 | NPSR1 (0.64) | PPARGABL1KDM5ACYP1B1ABCB1 | |
| SCHEMBL7303645 | 0.85 | CYP1B1 (0.57) | PPARGCYP1B1MAPT | |
| SCHEMBL7308871 | 0.84 | CYP1B1 (0.56) | PPARGCYP1B1MAPT | |
| SCHEMBL7310036 | 0.83 | CYP1B1 (0.55) | PPARGCYP1B1MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-5889003-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |