Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.70 |
| ▸ | CMA1 | P23946 | 6/20 | 0.59 |
| ▸ | CTSG | P08311 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300501 | 0.93 | ELANE (0.68) | ELANECMA1CTSG | |
| SCHEMBL7310232 | 0.89 | ELANE (0.80) | ELANECMA1CTSG | |
| SCHEMBL7432895 | 0.85 | ELANE (0.74) | ELANECMA1CTSG | |
| SCHEMBL7302317 | 0.83 | ELANE (1.00) | ELANECMA1CTSG | |
| SCHEMBL10081595 | 0.82 | ELANE (0.65) | ELANECMA1CTSG | |
| SCHEMBL7443048 | 0.82 | ELANE (0.68) | ELANECMA1CTSG | |
| SCHEMBL7303733 | 0.82 | ELANE (0.84) | ELANECMA1CTSG | |
| SCHEMBL3935563 | 0.81 | ELANE (0.67) | ELANECMA1CTSG | |
| SCHEMBL20943154 | 0.81 | ELANE (0.67) | ELANECMA1CTSG | |
| SCHEMBL20943188 | 0.81 | ELANE (0.67) | ELANECMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494071-B1 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5430025-A | Elastase-inhibiting peptides bearing a C-terminal trifluoromethylketone moiety | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |