Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298830 | 0.85 | ELANE (0.51) | ELANE | |
| SCHEMBL9298972 | 0.82 | ELANE (0.49) | ELANE | |
| SCHEMBL7284362 | 0.81 | ELANE (0.54) | ELANE | |
| SCHEMBL9298731 | 0.80 | ELANE (0.49) | ELANE | |
| SCHEMBL9298601 | 0.80 | ELANE (0.49) | ELANE | |
| SCHEMBL9298479 | 0.79 | ELANE (0.51) | ELANE | |
| SCHEMBL9299041 | 0.79 | ELANE (0.46) | ELANE | |
| SCHEMBL9298548 | 0.78 | ELANE (0.47) | ELANE | |
| SCHEMBL9299107 | 0.78 | ELANE (0.47) | ELANE | |
| SCHEMBL9299332 | 0.77 | ELANE (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | claimed |