Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298806 | 1.00 | SLC18A3 (0.40) | SLC18A3ESR2POLBPGRDDB1 | |
| SCHEMBL30909 | 0.83 | ESR2 (0.41) | ESR2POLBALDH1A1ESR1CYP3A4 | |
| SCHEMBL900534 | 0.82 | SLC18A3 (0.50) | SLC18A3ESR2POLBDDB1CRBN | |
| SCHEMBL1128088 | 0.82 | SLC18A3 (0.50) | SLC18A3ESR2POLBDDB1CRBN | |
| SCHEMBL5284 | 0.82 | SLC18A3 (0.50) | SLC18A3ESR2POLBDDB1CRBN | |
| SCHEMBL7733708 | 0.81 | KDM4E (0.39) | SLC18A3ESR2POLBKDM4EALDH1A1 | |
| SCHEMBL7733705 | 0.81 | KDM4E (0.39) | SLC18A3ESR2POLBKDM4EALDH1A1 | |
| Cyanide SCHEMBL27748394 | 0.81 | SLC18A3 (0.46) | SLC18A3ESR2POLBDDB1CRBN | |
| Hydrochloric Acid SCHEMBL20543303 | 0.80 | SLC18A3 (0.48) | SLC18A3ESR2POLBDDB1CRBN | |
| SCHEMBL11623457 | 0.80 | ESR2 (0.59) | ESR2ESR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657440-B1 | Oxazolidine-2-one derivatives as MAO inhibitors | HOFFMANN LA ROCHE (CH) | 2000-04-05 | — | — | EP | disclosed |
| US-5574055-A | COGNITIVE AND NEURODEGENERATIVE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0657440-A1 | Oxazolidine-2-one derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |