Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004780 | 0.88 | ELANE (0.66) | ELANE | |
| SCHEMBL7238810 | 0.87 | ELANE (0.65) | ELANE | |
| SCHEMBL7312357 | 0.84 | ELANE (0.70) | ELANE | |
| SCHEMBL7278147 | 0.81 | ELANE (0.69) | ELANE | |
| SCHEMBL7407054 | 0.81 | ELANE (0.66) | ELANE | |
| SCHEMBL7276065 | 0.81 | ELANE (0.71) | ELANE | |
| SCHEMBL9321418 | 0.79 | ELANE (1.00) | ELANE | |
| SCHEMBL9010433 | 0.79 | ELANE (0.74) | ELANE | |
| SCHEMBL9148980 | 0.78 | ELANE (0.62) | ELANE | |
| SCHEMBL8867762 | 0.78 | ELANE (0.73) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773456-A | EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS | SANOFI (FR) | 1998-06-30 | — | — | US | disclosed |
| US-5578623-A | DRUGS FOR TREATMENT OF ARTHRITIS, PANCREATITIS, CYSTIC FIBROSIS, BRONCHITIS, RESPIRATORY DISORDERS | STERLING WINTHROP INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5380737-A | Enzyme inhibitors | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0542371-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | disclosed |