Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.76 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.69 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.69 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.69 |
| ▸ | XDH | P47989 | 3/20 | 0.69 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | KDM1A | O60341 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 4/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | FLT3 | P36888 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311118 | 0.87 | CYP1B1 (0.57) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL7313615 | 0.87 | CYP1B1 (0.57) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL7316873 | 0.87 | CYP1B1 (0.57) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL7303645 | 0.87 | CYP1B1 (0.57) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL7306671 | 0.87 | CYP1B1 (0.57) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL30365934 | 0.87 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL29883103 | 0.87 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL2483636 | 0.87 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL7306096 | 0.86 | CYP1B1 (0.56) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 | |
| SCHEMBL7313588 | 0.86 | CYP1B1 (0.56) | CYP1B1CYP1A1CYP1A2IP6K2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-5889003-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |