Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056407 | 0.91 | LSS (0.61) | LSSLTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9482709 | 0.89 | KCNA3 (0.60) | LSSLTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10674690 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL10677919 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL10682923 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL10670983 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL10679393 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL10678308 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL10680527 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL10679619 | 0.88 | HDAC1 (0.60) | LSSHRH3KCNH2HRH1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874681-A | Indole derivative, preparation method thereof and application of indole derivative in resisting liver cancer | 中国人民解放军北部战区总医院 | 2025-04-25 | — | — | CN | disclosed |
| CN-115361948-A | Methods and compositions for inhibiting dihydroorotate dehydrogenase | 俄亥俄州国家创新基金会 | 2022-11-18 | — | — | CN | disclosed |
| EP-0931788-B1 | Metalloprotease inhibitors | PFIZER LTD (GB) | 2002-11-06 | — | — | EP | disclosed |
| US-6090852-A | MATRIX METALLOPROTEASE INHIBITOR | PFIZER INC (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0931788-A2 | Metalloprotease inhibitors | Pfizer Limited (GB) | 1999-07-28 | — | — | EP | disclosed |
| US-4973691-A | ANALGESICS | Spojene Podniky Prozdravotnickou Vyrobu (SPOFA) (CS) | 1990-11-27 | — | — | US | disclosed |