Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.75 |
| ▸ | CCR3 | P51677 | 2/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675291 | 0.83 | GBA1 (0.57) | GRIN2BCCR3ALDH1A1PRMT3CARM1 | |
| SCHEMBL2337033 | 0.82 | GRIN2B (0.71) | GRIN2BCCR3SLC18A3ALDH1A1PRMT3 | |
| Hydrochloric Acid SCHEMBL2335739 | 0.81 | GRIN2B (0.69) | GRIN2BCCR3SLC18A3ALDH1A1PRMT3 | |
| SCHEMBL13498072 | 0.79 | GRIN2B (0.72) | GRIN2BCCR3SLC18A3PRMT3CARM1 | |
| Bicarbonate SCHEMBL2854194 | 0.78 | GBA1 (0.52) | CCR3MEN1KMT2A | |
| SCHEMBL7301028 | 0.78 | SMN1; SMN2 (0.58) | KMT2A | |
| SCHEMBL3699320 | 0.77 | GBA1 (0.50) | GRIN2BCCR3SLC18A3 | |
| SCHEMBL6399920 | 0.76 | GBA1 (0.53) | GRIN2BCCR3SLC18A3PRMT3CARM1 | |
| Formic Acid SCHEMBL29099960 | 0.76 | GBA1 (0.49) | GRIN2BCCR3MEN1KMT2A | |
| SCHEMBL6398813 | 0.75 | GBA1 (0.52) | GRIN2BCCR3SLC18A3ALDH1A1PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153611-A | AS NON-DOPAMINERGIC ANTIISCHEMIC COMPOUNDS FOR TREATING BRAIN DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0546583-B1 | Piperazinyl-and piperidinyl-cyclohexanols | BRISTOL MYERS SQUIBB CO (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5478828-A | Anxiolytic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0560669-B1 | Piperazinyl-and piperidinyl-cyclohexenes and cyclohexanes | BRISTOL MYERS SQUIBB CO (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5387593-A | Anxiolytic agents | BRISTON-MYERS SQUIBB (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0560669-A1 | Piperazinyl-and piperidinyl-cyclohexenes and cyclohexanes | Bristol-Myers Squibb Company (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0546583-A1 | Piperazinyl-and piperidinyl-cyclohexanols | Bristol-Myers Squibb Company (US) | 1993-06-16 | — | — | EP | disclosed |