Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 17/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 17/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311914 | 0.81 | PDE3B (0.51) | PDE3BPDE3ALMNAKDM4E | |
| SCHEMBL7320379 | 0.80 | PDE3B (0.60) | PDE3BPDE3A | |
| SCHEMBL7311494 | 0.80 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7321627 | 0.80 | PDE3B (0.73) | PDE3BPDE3A | |
| SCHEMBL7305821 | 0.79 | PDE3B (0.53) | PDE3BPDE3A | |
| SCHEMBL7314397 | 0.77 | PDE3B (0.79) | PDE3BPDE3A | |
| SCHEMBL7314298 | 0.76 | PDE3B (0.68) | PDE3BPDE3A | |
| SCHEMBL7315793 | 0.75 | PDE3B (0.58) | PDE3BPDE3A | |
| SCHEMBL7310791 | 0.74 | PDE3B (0.49) | PDE3BPDE3ANPSR1PYGL | |
| SCHEMBL7311843 | 0.73 | PDE3B (0.46) | PDE3BPDE3APYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |