Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307176 | 0.81 | PREP (0.57) | PREPKMT2AMEN1ALDH1A1DPP4 | |
| SCHEMBL7302338 | 0.80 | PREP (0.67) | PREPKMT2A | |
| SCHEMBL7302343 | 0.80 | PREP (0.67) | PREPKMT2A | |
| SCHEMBL18281696 | 0.79 | PREP (0.62) | PREPKMT2AALDH1A1DPP4DPP7 | |
| SCHEMBL18296929 | 0.79 | PREP (0.59) | PREPALDH1A1DPP4DPP7DPP8 | |
| SCHEMBL25288720 | 0.77 | PREP (0.57) | PREPALDH1A1DPP4DPP7DPP8 | |
| SCHEMBL25288719 | 0.77 | PREP (0.57) | PREPALDH1A1DPP4DPP7DPP8 | |
| SCHEMBL25288721 | 0.77 | PREP (0.57) | PREPALDH1A1DPP4DPP7DPP8 | |
| SCHEMBL11764594 | 0.77 | PREP (0.71) | PREPKMT2AALDH1A1ACEFKBP1A | |
| SCHEMBL29874397 | 0.77 | PREP (0.71) | PREPKMT2AMEN1ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |