Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309692 | 0.86 | SETD7 (0.51) | SETD7S1PR5HRH1SIGMAR1CHRM3 | |
| SCHEMBL7300338 | 0.85 | SETD7 (0.64) | SETD7S1PR5HRH1SIGMAR1ATM | |
| SCHEMBL7300258 | 0.84 | SETD7 (0.52) | SETD7S1PR5HRH1SIGMAR1ATM | |
| SCHEMBL9035322 | 0.84 | SETD7 (0.66) | SETD7S1PR5HRH1SIGMAR1ATM | |
| SCHEMBL7307090 | 0.84 | SETD7 (0.52) | SETD7S1PR5HRH1SIGMAR1ATM | |
| SCHEMBL7309778 | 0.84 | SETD7 (0.66) | SETD7S1PR5HRH1SIGMAR1ATM | |
| Hydrochloric Acid SCHEMBL7213749 | 0.84 | SETD7 (0.62) | SETD7S1PR5HRH1SIGMAR1ATM | |
| SCHEMBL9034738 | 0.84 | SETD7 (0.66) | SETD7S1PR5HRH1SIGMAR1ATM | |
| SCHEMBL9034364 | 0.84 | SETD7 (0.66) | SETD7S1PR5HRH1SIGMAR1ATM | |
| Hydrochloric Acid SCHEMBL7217685 | 0.83 | SETD7 (0.65) | SETD7S1PR5HRH1SIGMAR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |