SCHEMBL730690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL733415	0.90	TSHR (0.46)	ACACBALDH1A1MAPTHPGDTSHR
	SCHEMBL14151406	0.90	ACACB (0.39)	ACACBHDAC3HDAC4HDAC1HDAC7
	SCHEMBL730568	0.90	TSHR (0.45)	ACACBALDH1A1MAPTHPGDTSHR
	SCHEMBL730567	0.90	TSHR (0.45)	ACACBALDH1A1MAPTHPGDTSHR
	SCHEMBL730824	0.90	TSHR (0.42)	ACACBHDAC3HDAC4HDAC1HDAC7
	SCHEMBL731943	0.89	ACACB (0.38)	ACACBHDAC3HDAC4HDAC1HDAC7
	SCHEMBL732641	0.81	HDAC3 (0.42)	ACACBHDAC3HDAC4HDAC1HDAC7
	SCHEMBL733374	0.77	HDAC3 (0.41)	ACACBHDAC3HDAC4HDAC1HDAC7
	SCHEMBL742125	0.77	TSHR (0.48)	ACACBHDAC3HDAC4HDAC1HDAC7
	SCHEMBL309173	0.77	ACACB (0.42)	ACACBALDH1A1HPGDHSD17B10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.