Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307000 | 1.00 | APP (0.46) | APPJUNNFKB1SETD7BCHE | |
| Hydrochloric Acid SCHEMBL9134059 | 0.99 | APP (0.45) | APPJUNNFKB1SETD7BCHE | |
| Hydrochloric Acid SCHEMBL9134058 | 0.99 | APP (0.45) | APPJUNNFKB1SETD7BCHE | |
| SCHEMBL7300478 | 0.86 | SETD7 (0.48) | APPSETD7ACHEKMT2AMEN1 | |
| SCHEMBL7300471 | 0.86 | SETD7 (0.48) | APPSETD7ACHEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9133561 | 0.85 | SETD7 (0.47) | APPSETD7ACHEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9133568 | 0.85 | SETD7 (0.47) | APPSETD7ACHEKMT2AMEN1 | |
| SCHEMBL7298141 | 0.85 | SETD7 (0.49) | SETD7KMT2AMEN1GAAMAPT | |
| SCHEMBL7298137 | 0.85 | SETD7 (0.49) | SETD7KMT2AMEN1GAAMAPT | |
| SCHEMBL7304872 | 0.84 | SETD7 (0.46) | SETD7KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |