Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318455 | 0.99 | KDM4E (0.47) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7317898 | 0.90 | MAPT (0.53) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7309450 | 0.87 | MAPT (0.52) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7314553 | 0.84 | KDM4E (0.48) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7318387 | 0.83 | KDM4E (0.46) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7318303 | 0.83 | KDM4E (0.47) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7320429 | 0.82 | KDM4E (0.45) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7314876 | 0.80 | MAOB (0.44) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL7306081 | 0.76 | PDE3B (0.46) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12238285 | 0.76 | MAPT (0.49) | KDM4EMEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |