Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.58 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.38 |
| ▸ | PDE2A | O00408 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311266 | 0.84 | PDE3B (0.80) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7320379 | 0.83 | PDE3B (0.60) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7313147 | 0.80 | PDE3B (0.86) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7314245 | 0.80 | PDE3B (0.71) | PDE3BPDE3AP2RY12PDE2APDE4A | |
| SCHEMBL7313434 | 0.79 | PDE3B (0.58) | PDE3BPDE3A | |
| SCHEMBL7316821 | 0.78 | PDE3B (0.57) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7316827 | 0.78 | PDE3B (0.57) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7312829 | 0.77 | PDE3B (0.94) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7319607 | 0.77 | PDE3B (0.94) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7307815 | 0.75 | PDE3B (0.72) | PDE3BPDE3AP2RY12PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |