Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306637 | 0.94 | PPARG (0.51) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7315470 | 0.93 | PPARG (0.51) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7307667 | 0.93 | PPARG (0.55) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7314642 | 0.92 | PPARG (0.54) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7307211 | 0.92 | PDE4A (0.54) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7306215 | 0.91 | KDM5A (0.55) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7304890 | 0.90 | PPARG (0.53) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7306656 | 0.90 | NPSR1 (0.59) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7317638 | 0.90 | PPARG (0.58) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7307612 | 0.90 | PPARG (0.58) | PPARGPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |