Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307245 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7307031 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7307025 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7302996 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7302989 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7301608 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7301607 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7304550 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7304553 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL7300827 | 0.82 | CCR3 (0.58) | SMN1; SMN2LMNAHTTCCR3PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |