⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260258 | 0.80 | — | — | |
| SCHEMBL7792316 | 0.76 | — | — | |
| SCHEMBL5807880 | 0.76 | — | — | |
| SCHEMBL10750833 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL7557616 | 0.74 | — | — | |
| SCHEMBL3832221 | 0.73 | — | — | |
| SCHEMBL27663767 | 0.73 | — | — | |
| SCHEMBL27510198 | 0.71 | — | — | |
| SCHEMBL10976488 | 0.71 | MAPT (0.30) | — | |
| SCHEMBL11591430 | 0.70 | APP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | disclosed |
| EP-0678503-A1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |