Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307426 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1TSHRCYP1A1CYP1A2 | |
| SCHEMBL7299185 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1TSHRCYP1A1CYP1A2 | |
| SCHEMBL7299179 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1TSHRCYP1A1CYP1A2 | |
| SCHEMBL7308580 | 0.89 | SETD7 (0.49) | KDM4EALDH1A1TSHRCYP1A1CYP1A2 | |
| SCHEMBL7308587 | 0.89 | SETD7 (0.49) | KDM4EALDH1A1TSHRCYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7218673 | 0.88 | SETD7 (0.48) | KDM4EALDH1A1TSHRCYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7218677 | 0.88 | SETD7 (0.48) | KDM4EALDH1A1TSHRCYP1A1CYP1A2 | |
| SCHEMBL7300481 | 0.80 | SETD7 (0.49) | KDM4EALDH1A1TSHRCYP1A2MAPK1 | |
| SCHEMBL7300479 | 0.80 | SETD7 (0.49) | KDM4EALDH1A1TSHRCYP1A2MAPK1 | |
| Hydrochloric Acid SCHEMBL7218909 | 0.80 | SETD7 (0.48) | KDM4EALDH1A1TSHRCYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |