Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947639 | 0.91 | F2 (0.55) | F2 | |
| SCHEMBL7308142 | 0.90 | F2 (0.46) | F2 | |
| SCHEMBL8947742 | 0.87 | F2 (0.41) | F2 | |
| SCHEMBL7306645 | 0.87 | F2 (0.41) | F2 | |
| SCHEMBL8947601 | 0.87 | F2 (0.62) | F2 | |
| SCHEMBL8947945 | 0.87 | F2 (0.73) | F2 | |
| Hydrochloric Acid SCHEMBL8947930 | 0.86 | F2 (0.74) | F2 | |
| SCHEMBL7306798 | 0.85 | F2 (0.45) | F2 | |
| Hydrochloric Acid SCHEMBL7306153 | 0.85 | F2 (0.55) | F2 | |
| SCHEMBL8947771 | 0.85 | F2 (0.51) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559046-B1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |