Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304510 | 0.95 | MAPK1 (0.39) | MAPK1L3MBTL1HTR2BPKMALDH1A1 | |
| SCHEMBL7313570 | 0.91 | MAPK1 (0.39) | MAPK1L3MBTL1HTR2BPKMALDH1A1 | |
| SCHEMBL7311133 | 0.91 | MAPK1 (0.41) | MAPK1L3MBTL1HTR2BGLACYP1A2 | |
| SCHEMBL7314702 | 0.88 | SMN1; SMN2 (0.38) | MAPK1L3MBTL1HTR2BPKMALDH1A1 | |
| SCHEMBL7311505 | 0.88 | HTR2B (0.44) | MAPK1L3MBTL1HTR2BGLACYP1A2 | |
| SCHEMBL7304061 | 0.87 | HTR2B (0.35) | MAPK1L3MBTL1HTR2BGLACYP1A2 | |
| SCHEMBL7310986 | 0.86 | HTR2B (0.36) | MAPK1L3MBTL1HTR2BPKMGLA | |
| SCHEMBL7307060 | 0.86 | MAPK1 (0.41) | MAPK1L3MBTL1HTR2BMEN1KMT2A | |
| SCHEMBL7317060 | 0.85 | MAPK1 (0.37) | MAPK1L3MBTL1HTR2BPKMGLA | |
| SCHEMBL7316784 | 0.84 | HTR2B (0.35) | MAPK1L3MBTL1HTR2BGLACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |