Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.49 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286468 | 0.83 | TYR (0.62) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL636139 | 0.83 | TYR (0.62) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL27737861 | 0.82 | MAPT (0.57) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL27737862 | 0.82 | MAPT (0.57) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL21807743 | 0.79 | TYR (0.71) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL21807742 | 0.79 | TYR (0.71) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL21647110 | 0.77 | TYR (0.72) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL21647133 | 0.77 | MAPT (0.68) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL29837044 | 0.77 | TYR (0.72) | TYRMAPTMAPK1MAOBKMT2A | |
| SCHEMBL21647126 | 0.77 | TYR (0.72) | TYRMAPTMAPK1MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947511-A1 | Derivatives of phenoxy acetic acid and of phenoxymethyl tetrazole having antitumor activity | F. HOFFMANN-LA ROCHE AG (CH) | 1999-10-06 | — | — | EP | disclosed |