Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.66 |
| ▸ | PPARG | P37231 | 5/20 | 0.64 |
| ▸ | CTSS | P25774 | 7/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007456 | 1.00 | PPARA (0.66) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL5007454 | 1.00 | PPARA (0.66) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL5007485 | 0.91 | PPARA (0.60) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL5007483 | 0.91 | PPARA (0.60) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL4997377 | 0.89 | PPARA (0.58) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL4997357 | 0.89 | PPARA (0.58) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL5007462 | 0.87 | PPARA (0.64) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL5007463 | 0.87 | PPARA (0.64) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL5001274 | 0.87 | PPARA (0.67) | PPARAPPARGCTSSACEPPARD | |
| SCHEMBL5001271 | 0.87 | PPARA (0.67) | PPARAPPARGCTSSACEPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |