Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306036 | 0.88 | EBP (0.41) | CHRM3EBPSIGMAR1CACNA1B | |
| SCHEMBL7308644 | 0.88 | EBP (0.35) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7317926 | 0.87 | EBP (0.35) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7309172 | 0.87 | EBP (0.35) | EBPSIGMAR1CACNA1B | |
| SCHEMBL8082767 | 0.87 | CHRM3 (0.38) | CHRM3ACHEEBPSIGMAR1SIRT2 | |
| SCHEMBL7302652 | 0.87 | EBP (0.37) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7316806 | 0.86 | EBP (0.37) | CHRM3EBPSIGMAR1POLBCACNA1B | |
| SCHEMBL7305376 | 0.86 | EBP (0.37) | CHRM3EBPSIGMAR1CACNA1B | |
| SCHEMBL7309476 | 0.86 | EBP (0.36) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7315131 | 0.86 | EBP (0.36) | EBPSIGMAR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |