Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 10/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312110 | 0.90 | KMT2A (0.37) | PDE3BPDE3AKMT2AMEN1GAA | |
| SCHEMBL7310679 | 0.85 | PDE3B (0.38) | PDE3BPDE3AALDH1A1MAPTCASP6 | |
| SCHEMBL7308660 | 0.84 | MEN1 (0.37) | PDE3BPDE3AKMT2AMEN1GAA | |
| SCHEMBL7311387 | 0.82 | PDE3B (0.40) | PDE3BPDE3AKMT2AGAAALDH1A1 | |
| SCHEMBL7308505 | 0.81 | PDE3B (0.42) | PDE3BPDE3AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10374470 | 0.81 | PDE3B (0.47) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10374494 | 0.80 | PDE3B (0.47) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7310470 | 0.80 | KMT2A (0.37) | PDE3BPDE3AKMT2AMEN1GAA | |
| SCHEMBL10374992 | 0.79 | PDE3B (0.39) | PDE3BPDE3AALDH1A1MAPTNPC1 | |
| SCHEMBL10375973 | 0.79 | PDE3B (0.47) | PDE3BPDE3APDE2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |