Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308731 | 1.00 | SETD7 (0.51) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7308496 | 0.87 | SETD7 (0.54) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7308498 | 0.87 | SETD7 (0.54) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7306260 | 0.87 | SETD7 (0.59) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7306252 | 0.87 | SETD7 (0.59) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL7295701 | 0.86 | SETD7 (0.58) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL7295705 | 0.86 | SETD7 (0.58) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7296028 | 0.85 | SETD7 (0.54) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7436166 | 0.85 | SETD7 (0.54) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7433819 | 0.85 | SETD7 (0.54) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |